[CITATION][C] Biosynthesis of diphosphopyridine nucleotide: II. Enzymatic aspects
J Preiss, P Handler - Journal of Biological Chemistry, 1958 - Elsevier
J Preiss, P Handler
Journal of Biological Chemistry, 1958•ElsevierIn the previous paper it was demonstrated that nicotinic acid-7-Cl4 is converted by human
erythrocytes and rat liver to nicotinic acid mononucleotide and nicotinic acid-adenine
dinucleotide (1). Evidence was also adduced that these two nucleotides are intermediate in
the synthesis of diphosphopyridine nucleotide (DPNI) from nicotinic acid. The present report
will describe preliminary studies of the three enzymes required to accomplish synthesis of
DPN from nicotinic acid as well as some data indicating the biological distribution of these …
erythrocytes and rat liver to nicotinic acid mononucleotide and nicotinic acid-adenine
dinucleotide (1). Evidence was also adduced that these two nucleotides are intermediate in
the synthesis of diphosphopyridine nucleotide (DPNI) from nicotinic acid. The present report
will describe preliminary studies of the three enzymes required to accomplish synthesis of
DPN from nicotinic acid as well as some data indicating the biological distribution of these …
In the previous paper it was demonstrated that nicotinic acid-7-Cl4 is converted by human erythrocytes and rat liver to nicotinic acid mononucleotide and nicotinic acid-adenine dinucleotide (1). Evidence was also adduced that these two nucleotides are intermediate in the synthesis of diphosphopyridine nucleotide (DPNI) from nicotinic acid. The present report will describe preliminary studies of the three enzymes required to accomplish synthesis of DPN from nicotinic acid as well as some data indicating the biological distribution of these enzymes.
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