Supercooling enables long-term transplantation survival following 4 days of liver preservation

TA Berendsen, BG Bruinsma, CF Puts, N Saeidi… - Nature medicine, 2014 - nature.com
TA Berendsen, BG Bruinsma, CF Puts, N Saeidi, OB Usta, BE Uygun, ML Izamis, M Toner
Nature medicine, 2014nature.com
The realization of long-term human organ preservation will have groundbreaking effects on
the current practice of transplantation. Herein we present a new technique based on
subzero nonfreezing preservation and extracorporeal machine perfusion that allows
transplantation of rat livers preserved for up to four days, thereby tripling the viable
preservation duration.
Abstract
The realization of long-term human organ preservation will have groundbreaking effects on the current practice of transplantation. Herein we present a new technique based on subzero nonfreezing preservation and extracorporeal machine perfusion that allows transplantation of rat livers preserved for up to four days, thereby tripling the viable preservation duration.
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